Drug Antibiotic Interactions-antimalarials
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چکیده
The antimicrobial effects of four antimalarials were determined. The effect of the chosen drugs when combined with a selected number of antibiotics was studied on Staphylococcus aureus and Escherichia coli to determine the types of interaction. Most antimalarials showed either no effect or a synergistic action. However, some exhibited antagonistic effects, which may be either due to some physical interaction or some unselective blockade of certain receptor sites essential to the action of antibiotics. (JPMA 36: 37, 1986).
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